When tragedy strikes Chief of Surgery Charlie Harris, his fiancee and fellow surgeon, Alex, races to save his life. Now in a coma, the doctor wanders the halls of the hospital in 'spirit' form, watching while Alex and the rest of the staff fight to keep their patients and hope alive.

Megan seems to have the perfect life with a wonderful husband named Thomas and two adorable children. When she awakens from a coma, Megan discovers she is not married, and never has been. But when she meets Thomas for real, she seizes the chance to help him fall in love with her again, for the first time.

Joe, a struggling truck driver, is haunted by the memory of his deceased wife and daughter. Joe's life takes a dramatic turn when he meets Julia, a woman with mysterious spiritual powers, whose daughter, Billie, lies in a coma. Julia enlists Joe's help to stop Billie from crossing over to the spirit world, but when Billie awakes, her body is possessed, by the vengeful spirit of Joe's dead wife.

Charlie is awake and he's still seeing spirits. This season we beg the question - can you change your fate? Charlie will battle to free himself of his connection to the spirit world, as it threatens to destroy his relationship with Alex, and even his life.