Karen Vail is on the trail of a serial killer with high-profile victims, and she must determine if the killer is connected to the disappearance of detective Robby Hernandez, Karen's boyfriend.

When a powerful firebomb destroys part of an art gallery in an exclusive London district, FBI Profiler Karen Vail is dispatched to England to work with Scotland Yard. But Vail soon discovers that at the heart of the bombing lies a 440-year-old manuscriptthat holds clues to England's past -- with content is so explosive that a group of political radicals is bent on destroying it at all costs.

When an elderly woman is found raped and brutally murdered in San Francisco, [FBI profiler Karen] Vail heads west to team up with SFPD Inspector Lance Burden and her former task force colleague, Detective Roxann Dixon. As Vail, Burden, and Dixon follow the killer's trail in and around San Francisco, the offender continues his rampage, leaving behind clues that ultimately lead them to the most unlikely of places: a mysterious island ripped from city...