The world's bestselling master of the medical thriller, Robin Cook skillfully combines human drama and high-tech thrills with the latest breakthroughs and controversies of modern medicine. Now, in his most daring novel yet, a mysterious transmission from the bottom of the Atlantic Ocean leads a crew of oceanographers and divers to a phenomenon beyond scientific understanding - a discovery that will change everything we know about life on Earth…...

Matthieu Zela is 256 years old in 1999, but doesn't look a day over 50. (Bafflingly, to himself, too, he simply stopped aging.) Loquacious Matthieu crisscrosses the centuries with wry, autobiographical narration, moving from his current incarnation as a satellite TV entrepreneur in London to his coming-of-age in the 1750s, when he leaves Paris for England with his young half-brother Tomas in tow and meets his one true love, Dominique Sauvet.

Key West, 2016. Sea levels are rising, coral reefs are dying. In short, everything is going to hell. It's here that two young filmmakers find something to believe in: an old sailor who calls himself Daniel Defoe and claims to be five hundred and sixty years old. In fact, old Dan is in the prime of his life -- an incredible, perhaps eternal American life. The story unfold over the course of a millennium, picking up in the sixteenth century in the Viceroyalty...