Twyla and Roberta have known each other since they were eight years old, roommates in the St. Bonaventure shelter. After losing touch, they meet several times by accident. Seemingly at opposite ends of every problem, and in disagreement each time they meet, the two cannot deny the deep bond their shared experience has forged between them.

"A revealing history of the West that pivots on Native peoples and the mixed families they made with European settlers. There is mixed blood at the heart of America. And at the heart of Native life for centuries there were complex households using marriage to link communities and protect people within circles of kin. These family circles took in European newcomers who followed the fur trade into Indian Country from the Great Lakes to the Columbia...

Luke Ransom was just eighteen years old when he answered an ad in a St. Louis newspaper that would change his life forever. The American Fur Company needed one-hundred enterprising men to travel up the Missouri River -- the longest in North America -- all the way to its source. They would hunt and trap furs for one, two, or three years. Along the way, they would face unimaginable hardships: grueling weather, wild animals, hunger, exhaustion, and hostile...